琥珀酸二乙酯及丁酸乙酯具有無毒、溶解性好、不易揮發、有果香味等特點，是重要的合成香料和食品添加劑，廣泛用於食品、香料、醫藥、日用化工、塗料等工業。本論文探討使用各種混合金屬氧化物觸媒，改變反應溫度、反應時間來催化琥珀酸及丁酸與乙醇間的酯化反應以製造琥珀酸二乙酯及丁酸乙酯。在琥珀酸酯化反應中，TiO2- SiO2觸媒有最好之催化琥珀酸酯化的性能，琥珀酸二乙酯之最高產率為98.11％(210℃，6hr)。在丁酸酯化反應中，TiO2- SiO2觸媒有最好之催化丁酸酯化的能力，丁酸乙酯之最高產率為97.47％(170℃，6hr)。本研究使用共沉澱法製備不同莫耳比的TiO2-ZrO2觸媒、TiO2-Al2O3觸媒、ZrO2-Al2O3觸媒及TiO2-SiO2觸媒，利用X射線繞射儀(XRD)、熱場發射掃描式電子顯微鏡(TFSEM)、熱重分析儀(TGA)、表面積與孔洞分析儀（BET）、能量散射光譜儀(EDS)對各種混合金屬氧化物觸媒作特性分析。 Diethyl succinate and ethyl butyrate are because of their non-toxic, good solubility, less volatile, fruit flavor, and other characteristics, are important synthetic spices and food additives.They are widely used in food,spices,pharmaceuticals,household chemicals and paint industries.This thesis studies the effects of mixed metal oxide catalysts, reaction temperature, reaction time on the esterification of succinic acid and butyric acid with ethanol to produce diethyl succinate and ethyl butyrate. For the succinic acid esterification,TiO2-SiO2 catalyst had the best catalytic perfornance with the maximum diethyl succinate yield of 98.11％ at 210℃ and 6hr. For the butyric acidesterification,TiO2-SiO2 catalyst had the best catalytic performance with the maximum ethyl butyrate yield of 97.47％ at 170℃ and 6hr.XRD、TFSEM、TGA、BET and EDS were used to characterize TiO2-ZrO2,TiO2-Al2O3,ZrO2-Al2O3 ,TiO2-SiO2 catalysts which were prepared by a co-precipitation method.
