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Please use this identifier to cite or link to this item:
http://140.128.103.80:8080/handle/310901/21037
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| Title: | Pregnancy-induced hemophagocytic lymphohistiocytosis combined with autoimmune hemolytic anemia |
| Authors: | Teng, C.-L.ae, Hwang, G.-Y.e, Lee, B.-J.b, Wang, R.-C.c, Chou, M.-M.d |
| Contributors: | Department of Life Science, Tunghai University |
| Keywords: | Hemolysis;Hemophagocytosis;Pregnancy |
| Date: | 2009 |
| Issue Date: | 2013-05-14T09:00:15Z (UTC)
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| Abstract: | Hemophagocytic lymphohistiocytosis (HLH), presenting with fever, cytopenia, liver dysfunction, hepatosplenomegaly, hypertriglyceridemia, and hyperferritinemia, is associated with various etiologies, including infections, collagen vascular diseases, and malignancies. The present report describes a 28-year-old woman who developed HLH combined with autoimmune hemolytic anemia (AIHA) at 23 weeks of gestation. Without response to corticosteroid, the patient completely recovered from both HLH and AIHA after termination of the pregnancy. Pregnancy-induced immune dysregulation and cytokine overproduction in genetically susceptible women may play critical roles in HLH. The differential diagnosis of pregnant women with fever and cytopenia should include HLH. Pregnancy termination should be considered when pregnancy-induced HLH is refractory to medical treatment. ? 2009 Elsevier. All rights reserved. |
| Relation: | Journal of the Chinese Medical Association
Volume 72, Issue 3, March 2009, Pages 156-159 |
| Appears in Collections: | [生命科學系所] 期刊論文
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