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http://140.128.103.80:8080/handle/310901/21404
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| Title: | Characterization of benign and malignant solid breast masses in harmonic 3D power Doppler imaging |
| Authors: | Hsiao, Y.-H.a, Huang, Y.-L.b, Kuo, S.-J.c, Liang, W.-M.d, Chen, S.-T.c , Chen, D.-R. |
| Contributors: | Department of Computer Science, Tunghai University |
| Keywords: | Flow index;Harmonic three-dimensional power Doppler;Vascularization index;Vascularization-flow index |
| Date: | 2009 |
| Issue Date: | 2013-05-14T09:05:58Z (UTC)
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| Abstract: | Purpose: The authors assessed the characteristics of benign and malignant solid breast tumors in harmonic three-dimensional (3D) power Doppler imaging and proposed decision models to classify benign and malignant breast tumors. Materials and methods: A total of 86 malignant and 97 benign harmonic 3D power Doppler US images were analyzed. All the harmonic 3D power Doppler images were obtained using a Voluson730 US system (GE, Zipf, Austria) equipped with a RSP 6-12 transducer and tissue harmonic imaging modalities. Imaging analysis was performed using the Virtual Organ Computer-aided Analysis (VOCAL)-imaging program. Histogram indices, the vascularization index (VI), flow index (FI) and vascularization-flow index (VFI), were calculated for the intra-tumor and for shells with an outside thickness of 3 mm surrounding the breast tumors. The receiver operating characteristic (ROC) curves were calculated to estimate the diagnostic performances. Results: The results revealed that the choice of decision model comprised the parameters of patient age, intra-tumor VI, and tumor volume to classify benign and malignant breast tumors. The area under the ROC curve (Az) was 0.910, accuracy was 81.4%, and sensitivity and specificity were 81.4% and 81.4%, respectively. The parameter intra-tumor VI was the choice for all of the histogram indices in differentiating between malignant and benign lesions. Conclusion: The decision model, which was composed of patient age, tumor volume and intra-tumor VI, and a cut-off value for intra-tumor VI at the upper end of patient age and tumor volume, was recommended in clinical application. ? 2008 Elsevier Ireland Ltd. All rights reserved. |
| Relation: | European Journal of Radiology
Volume 71, Issue 1, July 2009, Pages 89-95 |
| Appears in Collections: | [資訊工程學系所] 期刊論文
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